Rabbit hemorrhagic disease virus (RHDV2) is a highly contagious and usually fatal disease in rabbits. As of early 2023, RHDV had not recently been identified in Indiana, but many states have seen cases, both in wild cottontail rabbits, and in pet rabbits. In many cases of the disease in pet rabbits, the source of the virus is not determined. The virus is extremely contagious, and can be transmitted not only from rabbit to rabbit, but on food, in water, or other contaminated materials.

A vaccination for the virus has existed for many years in Europe and other parts of the world, but not in the US. In October 2021, a vaccine manufacturing company in the US (MedGene) received emergency authorization from the USDA to offer a vaccine. 

The vaccine has been found 100% effective, and safe during trials in healthy young experimental rabbits. Side effects included some cases of slight fever, lethargy, and swelling at the site of the injection. It should be kept in mind that more serious side effects may be identified as larger numbers of pet rabbits of various ages and health status receive the vaccine.  

The vaccine can be used in rabbits as young as 4 weeks of age, and requires a single dose, followed by a booster in 21 days. According to the manufacturer, rabbits should be fully protected two weeks after the booster vaccine, and then revaccinated yearly.

More information can be found on Medgene’s website: https://medgenelabs.com/rhdv2/